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No clinical implications from Drosophila model; leaves open evolutionary insights into visceral striated muscle.
Striated visceral muscle cells are scattered singly or in small groups at the base of the intestinal cells of the mid‐gut of Drosophila melanogaster larvae. Fibers less than 1 μ in diameter, designated as small, contain a single myofibril, few, if any, dyads and few mitochondria. Fibers of somewhat larger diameter contain dyads and more mitochondria. Both types of fiber have a perforate Z band which appears as discontinuous bodies in longitudinal sections and as a perforate sheet of dense rims and clear perforations in transverse sections. The Z rims contain filaments, 30 to 50 Å, oriented in the transverse direction. The number and arrangement of myofilaments and the ultrastructure of the Z band are consistent with the function of these muscles.
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Goldstein et al. (1971) studied this question.
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