Why the study?
Although striated muscle thick filament motor domain structure and function are well understood, the structure of the myosin filament backbone is not.
Population
Flight muscle thick filaments from Drosophila melanogaster
Design
Structural biology study at 4.7 Å resolution
Authors
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Should not yet change practice; leaves open whether flightin–myofilin packing rules apply to cardiac thick-filament assembly.
Key points are not available for this paper at this time.
Yeganeh et al. (2023) studied this question.
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