Why the study?
Does intraoperative left atrial epicardial cryoablation improve rhythm outcome and affect cardiac function in patients with coronary artery disease and atrial fibrillation undergoing CABG?
Population
70 patients with coronary artery disease and documented atrial fibrillation undergoing coronary artery…
Comparison
Intraoperative left atrial epicardial… vs Coronary artery bypass surgery alone
Design
Cohort
Follow-up
22 ± 6 months
Key result
Intraoperative left atrial epicardial cryoablation during coronary artery bypass surgery significantly increased the proportion of patients in sinus rhythm at 22 months to 63%, compared to 34% with surgery alone.
Authors
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May support cryoablation for sinus rhythm after CABG with AF; leaves open net benefit given functional changes and needs RCTs.
Case-Control (n=70)
Single-blind (outcome assessors)
No
Does intraoperative left atrial epicardial cryoablation improve rhythm outcome and affect cardiac function in patients with coronary artery disease and atrial fibrillation undergoing CABG?
Absolute Event Rate: 63% vs 34%
p-value: p=0.04
Concomitant epicardial left atrial cryoablation during CABG significantly increases the proportion of patients in sinus rhythm at approximately 2 years, though it is associated with mild decreases in atrial and ventricular function.
Johansson et al. (2011) conducted a case-control in Coronary artery disease and atrial fibrillation (n=70). Intraoperative left atrial epicardial cryoablation vs. Coronary artery bypass grafting (CABG) alone was evaluated on Proportion of patients in sinus rhythm at long-term follow-up (p=0.04). Intraoperative left atrial epicardial cryoablation during coronary artery bypass surgery significantly increased the proportion of patients in sinus rhythm at 22 months to 63%, compared to 34% with surgery alone.
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