Parallel Morning and Evening Surge in Stroke Onset, Blood Pressure, and Physical Activity
Key result
Diurnal variation in stroke onset, blood pressure, and pulse rate exhibited parallel morning and evening peaks corresponding to physical activity patterns (P<0.001).
Why the study?
Is the diurnal variation of stroke onset associated with the diurnal variation of blood pressure, pulse rate, and physical activity in hypertensive patients?
Population
1,062 Greek hypertensives aged 51 to 80 years, comprising 3 independent groups: 633 stroke patients, 379…
Design
Cross-sectional
Authors
Discussion
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Implication
May link activity-driven BP surges to stroke timing in hypertensives; hypothesis-generating for timed prevention trials.
Study Design
Type
Observational (n=1,062)
Structured PICO
Is the diurnal variation of stroke onset associated with the diurnal variation of blood pressure, pulse rate, and physical activity in hypertensive patients?
P
Population
1,062 Greek hypertensive patients aged 51 to 80 years, evaluated across three independent groups for stroke onset, 24-hour ambulatory BP, and 24-hour physical activity.
O
Outcome
Diurnal variation of stroke onset, blood pressure, pulse rate, and physical activityhard clinical
Main Result
p-value: p=<0.001
The two-peak diurnal variation in stroke onset parallels changes in physical activity and blood pressure, suggesting abrupt physical activity changes may trigger cerebrovascular events.
Cite This Study
Stergiou et al. (2002) conducted an observational in Hypertension and Stroke (n=1,062). Time of day and physical activity vs. Different time intervals (morning, afternoon, evening, nighttime) was evaluated on Differences among morning, afternoon, evening, and nighttime intervals in BP, PR, activity, and stroke (p=<0.001). Diurnal variation in stroke onset, blood pressure, and pulse rate exhibited parallel morning and evening peaks corresponding to physical activity patterns (P<0.001).