Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 1, 1983Comprehensive physiology

Mechanism of Ca 2+ Transport by Sarcoplasmic Reticulum

View Full Paper
Ask AI
Bookmark
Share

Authors

AMAnthony MartonosiPurchase CollegeTBTroy BeelerUniformed Services University of the Health Sciences

Discussion

Loading...

Member takes

Overview

This article explores calcium transport mechanisms in skeletal muscle, highlighting structural and functional insights.

Key Points

  • This research examines the mechanisms underlying calcium transport by the sarcoplasmic reticulum in skeletal muscle cells.
  • Isolation and study of membrane fractions from skeletal muscle including SR and T tubules.
  • Analysis of protein composition and lipid structures within the sarcoplasmic reticulum.
  • Kinetic studies of ATP hydrolysis and calcium binding measurements.
  • Characterized the primary sequence and structure of calcium transport ATPase from rabbit sarcoplasmic reticulum.
  • Identified the roles of phospholipids and calsequestrin in modulating calcium transport efficiency.
  • Demonstrated the mechanism of enzyme phosphorylation influencing calcium translocation.

Cite This Study

Martonosi et al. (1983) studied this question.

synapsesocial.com/papers/6a204b4b89a9728653d1e478https://doi.org/10.1002/j.2040-4603.1983.tb01666.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transient state kinetic studies of sarcoplasmic reticulum adenosine triphosphatase.1975 · 217 citations
  2. 2Control of muscle contraction1969 · 795 citations
  3. 3Factors Affecting the Transient Phase of the Ca2+, Mg2+-Dependent1978 · 31 citations
  4. 4Organization of Lipids in Sarcoplasmic Reticulum Membrane and Ca2+-dependent ATPase Activity1975 · 54 citations
  5. 5Localization of the high affinity calcium binding protein and an intrinsic glycoprotein in sarcoplasmic reticulum membranes.1980 · 138 citations