Key result
The Ultegra point-of-care analyzer demonstrated 87% overall agreement and a correlation of 0.902 with conventional aggregometry for assessing aspirin responsiveness.
Why the study?
Does the point-of-care Ultegra rapid platelet function analyzer validly measure aspirin responsiveness compared to conventional aggregometry in subjects with multiple risk factors for CAD?
Population
148 subjects with multiple risk factors for coronary artery disease
Comparison
One pill of non-enteric coated aspirin (325 mg) vs Baseline (pre-aspirin)
Design
Cohort
Follow-up
2-30 hours
Authors
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May support rapid aspirin responsiveness testing in CAD; leaves open outcome validation versus conventional methods.
Observational (n=148)
Yes
Does the point-of-care Ultegra rapid platelet function analyzer validly measure aspirin responsiveness compared to conventional aggregometry in subjects with multiple risk factors for CAD?
The Ultegra rapid platelet function analyzer is a valid and fast point-of-care method for assessing aspirin responsiveness, showing high agreement with conventional aggregometry.
Malinin et al. (2004) conducted an observational in Multiple risk factors for coronary artery disease (n=148). Ultegra analyzer vs. Conventional aggregometry was evaluated on Overall agreement between Ultegra analyzer and conventional aggregometry. The Ultegra point-of-care analyzer demonstrated 87% overall agreement and a correlation of 0.902 with conventional aggregometry for assessing aspirin responsiveness.
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