Key result
Childhood BMI significantly predicted increased carotid intima media thickness in adulthood (OR 3.39), but had only a weak ability to predict adult atherosclerotic cardiovascular disease events (OR 1.04).
Why the study?
Do measures of childhood obesity predict dysglycaemia and adult atherosclerotic cardiovascular disease?
Population
18 studies examining the ability of measures of obesity in childhood to predict dysglycaemia and adult…
Design
Meta-analysis
Follow-up
Childhood to adulthood
Authors
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Childhood BMI may not guide ACVD prevention decisions; confirms strong CIMT links but leaves clinical event prediction open.
Meta-Analysis (n=317,133)
Do measures of childhood obesity predict dysglycaemia and adult atherosclerotic cardiovascular disease?
Odds Ratio: 3.39 (95% CI 2.02–5.67)
p-value: p=<0.001
Childhood BMI is a strong predictor of adult dysglycaemia and abnormal CIMT, but only a weak-to-moderate predictor of clinical ACVD events and hypertension.
Ajala et al. (2017) conducted a meta-analysis in Cardiovascular disease and dysglycemia (n=317,133). Childhood Body Mass Index (BMI) vs. Lower childhood BMI was evaluated on Carotid intima media thickness (CIMT) in adulthood (OR 3.39, 95% CI 2.02-5.67, p=<0.001). Childhood BMI significantly predicted increased carotid intima media thickness in adulthood (OR 3.39), but had only a weak ability to predict adult atherosclerotic cardiovascular disease events (OR 1.04).
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