Key result
Metabolic syndrome was associated with a significantly higher prevalence of increased carotid intima-media thickness compared to patients without metabolic syndrome (72.4% vs 38.1%, p=0.033) in patients with ischemic stroke.
Why the study?
Metabolic syndrome increases the risk of atherosclerotic diseases and is associated with increased carotid intima-media thickness, but the correlation between metabolic syndrome and increased carotid intimal media thickness warranted further evaluation.
Does metabolic syndrome correlate with increased carotid intima-media thickness in patients with ischemic stroke?
Cross-Sectional (n=50)
No
Does metabolic syndrome correlate with increased carotid intima-media thickness in patients with ischemic stroke?
Absolute Event Rate: 72.4% vs 38.1%
p-value: p=0.033
In patients with ischemic stroke, the presence of metabolic syndrome is significantly associated with increased carotid intima-media thickness, suggesting Carotid Doppler is a useful screening tool for atherosclerosis in this population.
Association supports considering metabolic syndrome in stroke-related carotid assessment; hypothesis-generating and should not yet change practice.
Background: Metabolic syndrome and its individual criteria poses an increased risk for atherosclerotic diseases. Metabolic syndrome is also associated with increase in carotid intima-media thickness, which is a marker of preclinical atherosclerosis. Hence this study was aimed to determine to find out correlation between metabolic syndrome and increase in carotid intimal media thickness. Methods: All patients with stroke age more 30 years admitted in Department of General Medicine during the study period from May 2017 to April 2020 were included in study. A total of 50 patients presenting with stroke were assessed and were classified as metabolic syndrome or non-metabolic syndrome based on IDF criteria who fulfilled the selection criteria during the study period were enrolled. Results: Out of 50 stroke patients studied, 29 patients (17 males and 12 females) had metabolic syndrome according to IDF criterion. Occurrence of metabolic syndrome in patients with stroke was 58%. Out of total 29(58%) patients with metabolic syndrome, 17(58.6%) were male and 12(57.1%) patients were. Out of total patients in the study group, 29 patients had increased carotid intimal thickness out of which 21(72.4%) patients had metabolic syndrome with 12(75%) Males and 09(69.23%) Females. It was found to be statistically significant with p value 0.03. Conclusions: Accelerated rate of atherosclerosis in found in patients with metabolic syndrome and there is increase in CIMT in these patients, so carotid doppler can be used for predicting atherosclerotic changes in such patients in early stages.
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Dr Vaja Mukhtarahmed (2019) conducted a cross-sectional in Ischemic stroke and Metabolic Syndrome (n=50). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Increased carotid intima-media thickness (>0.1 cm) (p=0.033). Metabolic syndrome was associated with a significantly higher prevalence of increased carotid intima-media thickness compared to patients without metabolic syndrome (72.4% vs 38.1%, p=0.033) in patients with ischemic stroke.
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