Why the study?
Is the presence of metabolic syndrome and type 2 diabetes associated with increased carotid intima-media thickness?
Population
918 patients evaluated for metabolic syndrome using modified Japanese criteria.
Comparison
Presence of metabolic syndrome, type 2 diabetes… vs Patients with no metabolic abnormalities.
Design
Cross-sectional
Authors
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May inform risk stratification in combined metabolic syndrome and diabetes; leaves open causal inference and need for prospective outcome trials.
Is the presence of metabolic syndrome and type 2 diabetes associated with increased carotid intima-media thickness?
Metabolic syndrome and type 2 diabetes are independently and synergistically associated with increased carotid intima-media thickness, a surrogate marker for subclinical atherosclerosis.
Kawamoto et al. (2007) studied this question.
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