Key result
Metabolic syndrome is linked to more carotid plaques and IMT > 0.80 mm in asymptomatic participants.
Why the study?
Is metabolic syndrome associated with increased carotid intima-media thickness and carotid plaques in asymptomatic individuals?
Population
479 asymptomatic participants from the ISMIR study, including 80 participants with metabolic syndrome.
Comparison
Metabolic syndrome (MetS) vs Participants without metabolic syndrome
Design
Cross-sectional
Authors
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May signal higher subclinical carotid atherosclerosis risk with metabolic syndrome; leaves open need for longitudinal outcome confirmation.
Cross-Sectional (n=479)
Is metabolic syndrome associated with increased carotid intima-media thickness and carotid plaques in asymptomatic individuals?
p-value: p=0.004 for IMT > 0.80 mm; <0.001 for plaques
Metabolic syndrome is significantly associated with early markers of carotid atherosclerosis, including increased intima-media thickness and plaques, in asymptomatic individuals.
Antonini‐Canterin et al. (2010) conducted a cross-sectional in Metabolic syndrome (n=479). Metabolic syndrome vs. Participants without metabolic syndrome was evaluated on Prevalence of carotid IMT > 0.80 mm and carotid plaques (p=0.004 for IMT > 0.80 mm; <0.001 for plaques). Metabolic syndrome was associated with a significantly higher prevalence of carotid IMT > 0.80 mm (P=0.004) and carotid plaques (P<0.001) in asymptomatic participants.