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August 20, 2013Diabetology & Metabolic SyndromeOpen Access

Association between presence of the metabolic syndrome and its components with carotid intima-media thickness and carotid and femoral plaque area: a population study

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Why the study?

Is the presence and number of components of Metabolic Syndrome associated with increased carotid and femoral subclinical atherosclerosis in a general population?

Population

771 volunteers from the epidemiological Cyprus Study, mean age 60.1 ± 9.8, 46% male.

Comparison

Presence and number of components of the… vs Absence of MetS or fewer components

Design

Cross-sectional

Authors

APAndrie G. PanayiotouCyprus University of TechnologyMGMaura GriffinArizona Heart InstitutePΚPanayiotis ΚouisCyprus University of Technology

Discussion

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Implication

MetS and component count were associated with greater subclinical atherosclerosis; leaves open causal role and need for prospective validation.

Structured PICO

Is the presence and number of components of Metabolic Syndrome associated with increased carotid and femoral subclinical atherosclerosis in a general population?

P
Population
771 volunteers from the epidemiological Cyprus Study, mean age 60.1 ± 9.8, 46% male.
I
Intervention
Presence and number of components of the Metabolic Syndrome (MetS) defined by NCEP ATPIII
C
Comparator
Absence of MetS or fewer components
O
Outcome
Subclinical atherosclerosis outcomes including common carotid intima media thickness (IMTcc), plaque presence, and sum of plaque area in carotid and femoral bifurcations measured by ultrasoundsurrogate

The presence of Metabolic Syndrome and an increasing number of its components are associated with greater subclinical atherosclerosis in both carotid and femoral arteries in a general population over 40 years of age.

Cite This Study

Panayiotou et al. (2013) studied this question.

synapsesocial.com/papers/6a70db106c240de38cdbf760https://doi.org/10.1186/1758-5996-5-44
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Metabolic Syndrome and Subclinical Carotid Atherosclerosis: The Northern Manhattan Study2007 · 45 citations
  2. 2Carotid Atherosclerosis Is a Stronger Predictor of Myocardial Infarction in Women Than in Men2007 · 402 citations
  3. 3Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris2001 · 194 citations
  4. 4The Metabolic Syndrome, Its Component Risk Factors, and Progression of Coronary Atherosclerosis2010 · 149 citations
  5. 5Common Carotid Intima-Media Thickness and Risk of Stroke and Myocardial Infarction1997 · 2,354 citations