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September 1, 1977AJP Cell Physiology

Contractile properties of rat soleus muscle: effects of training and fatique

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Why the study?

Does prolonged exercise training alter the contractile properties and fatigue resistance of rat soleus muscles?

Population

Rat soleus muscles

Comparison

Prolonged exercise training and fatigue protocol vs Untrained animals

Design

Preclinical

Authors

RFR. H. FittsMarquette UniversityJHJ. O. HolloszyBrigham Young University

Discussion

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Overview

Does not support clinical exercise changes; leaves open translation of rat soleus adaptations to humans.

Structured PICO

Does prolonged exercise training alter the contractile properties and fatigue resistance of rat soleus muscles?

P
Population
Rat soleus muscles
I
Intervention
Prolonged exercise training (2 h of daily treadmill running) and fatigue protocol (in situ stimulation with 250-ms trains of 100 Hz at 110 trains/min for 30 min)
C
Comparator
Untrained animals
O
Outcome
Contractile properties including contraction time, one-half relaxation time, maximum tetanic tension (Po), peak rate of tension development (dP/dt), and maximum shortening velocity (Vmax)surrogate

Prolonged exercise training modifies the neurally determined contractile properties of skeletal muscle and protects against fatigue-induced declines in tension and shortening velocity.

Cite This Study

Fitts et al. (1977) studied this question.

synapsesocial.com/papers/6a204edde9ca693ff1e71faahttps://doi.org/10.1152/ajpcell.1977.233.3.c86
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