Single breathhold multi-echo 3D hybrid radial SSFP acquisition yielded cardiac function measurements highly correlated with conventional 2D multiple breathhold exams (r=0.91-0.97) with minimal bias.
8 healthy volunteers undergoing cardiac CINE imaging to validate a new single breathhold 3D MRI technique.
Multi-echo 3D hybrid radial SSFP acquisition vs Conventional 2D multiple breathhold technique
Left ventricle functional measurement bias (end diastolic volume, end systolic volume, and ejection fraction) — EDV bias -3.3 ± 13.7 mL, ESV bias 1.4 ± 6.1 mL, EF bias -1.7% ± 4.3%
Effect estimate: EDV bias -3.3 ± 13.7 mL, ESV bias 1.4 ± 6.1 mL, EF bias -1.7% ± 4.3%
PURPOSE: To achieve single breathhold whole heart cardiac CINE imaging with improved spatial resolution and temporal resolution by using a multi-echo three-dimensional (3D) hybrid radial SSFP acquisition. MATERIALS AND METHODS: Multi-echo 3D hybrid radial SSFP acquisitions were used to acquire cardiac CINE imaging within a single breathhold. An optimized interleaving scheme was developed for view ordering throughout the cardiac cycle. RESULTS: Whole heart short axis views were acquired with a spatial resolution of 1.3 x 1.3 x 8.0 mm(3) and temporal resolution of 45 ms, within a single 17 s breathhold. The technique was validated on eight healthy volunteers by measuring the left ventricular volume throughout the cardiac cycle and comparing with the conventional 2D multiple breathhold technique. The left ventricle functional measurement bias of our proposed 3D technique from the conventional 2D technique: end diastolic volume -3.3 mL +/- 13.7 mL, end systolic volume 1.4 mL +/- 6.1 mL, and ejection fraction -1.7% +/- 4.3%, with high correlations 0.94, 0.97, and 0.91, accordingly. CONCLUSION: A multi-echo 3D hybrid radial SSFP acquisition was developed to allow for a whole heart cardiac CINE exam in a single breathhold. Cardiac function measurements in volunteers compared favorably with the standard multiple breathhold exams.
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Jing Liu
Oliver Wieben
Cardiac Imaging
Youngkyoo Jung
University of California Davis Medical Center
Journal of Magnetic Resonance Imaging
Cornell University
University of California, San Diego
University of Wisconsin–Madison
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Liu et al. (Thu,) conducted a other in Healthy volunteers (n=8). Multi-echo 3D hybrid radial SSFP acquisition vs. Conventional 2D multiple breathhold technique was evaluated on Left ventricle functional measurement bias (end diastolic volume, end systolic volume, and ejection fraction) (EDV bias -3.3 ± 13.7 mL, ESV bias 1.4 ± 6.1 mL, EF bias -1.7% ± 4.3%). Single breathhold multi-echo 3D hybrid radial SSFP acquisition yielded cardiac function measurements highly correlated with conventional 2D multiple breathhold exams (r=0.91-0.97) with minimal bias.
synapsesocial.com/papers/6a204f0312b97f18eeb834e1 — DOI: https://doi.org/10.1002/jmri.22269
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