Why the study?
Are plasma fibrinogen, C-reactive protein, and G-455>A polymorphism associated with early atherosclerosis?
Population
2,580 subjects from the VITA Project cohort
Comparison
Plasma fibrinogen levels, fibrinogen… vs Subjects with lower fibrinogen levels or…
Design
Cross-sectional
Authors
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Persistent fibrinogen elevation may mark early carotid atherosclerosis; hypothesis-generating and requires prospective validation before clinical use.
Are plasma fibrinogen, C-reactive protein, and G-455>A polymorphism associated with early atherosclerosis?
A persistent increase in plasma fibrinogen is associated with an increased risk of early atherosclerosis, as evidenced by the presence of carotid plaques.
Tosetto et al. (2010) studied this question.
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