Sequential serum creatine kinase determination differentiates vaso-vagal syncope from generalized tonic-clonic seizures

33 patients, including 16 with first generalized tonic-clonic seizure (GTCS) (age 31 +/- 11 years, 8 women) and 17 with vaso-vagal syncope (VVS) (age 32 +/- 13 years, 8 women). Patients with physical injuries were excluded.

Sequential serum creatine kinase (CK) determination at admission to the emergency room and 24-26 h later

Diagnostic accuracy (sensitivity and specificity) of CK levels and their change over 24-26 hours to differentiate GTCS from VVSsurrogate