Key result
Postictal serum creatine kinase elevations occurred in 50% of patients with generalized tonoclonic seizures compared to 0% of patients with psychogenic or other seizure types.
Why the study?
Does daily serum creatine kinase measurement help differentiate between psychogenic and epileptic generalized tonoclonic seizures in hospitalized patients?
Population
22 hospitalized patients with different types of epileptic and nonepileptic seizures documented by video EEG…
Design
Cohort
Authors
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Postictal CK may support differentiation of GTCS from psychogenic seizures; leaves open need for prospective validation.
Observational (n=22)
Does daily serum creatine kinase measurement help differentiate between psychogenic and epileptic generalized tonoclonic seizures in hospitalized patients?
Absolute Event Rate: 50% vs 0%
Postictal CK determination can serve as an adjunctive test for differentiation between psychogenic and epileptic generalized tonoclonic seizures.
Wyllie et al. (1985) conducted an observational in Seizure disorders (n=22). Generalized tonoclonic seizures vs. Psychogenic and other epileptic seizures was evaluated on Postictal serum creatine kinase (CK) elevations. Postictal serum creatine kinase elevations occurred in 50% of patients with generalized tonoclonic seizures compared to 0% of patients with psychogenic or other seizure types.
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