Key result
Systemic lupus erythematosus was independently associated with increased arterial stiffness in the common carotid artery (P=0.01) and popliteal artery (P=0.005) compared to healthy controls.
Why the study?
Does systemic lupus erythematosus increase arterial stiffness in postmenopausal women without manifest cardiovascular disease?
Population
94 postmenopausal women, comprising 39 with systemic lupus erythematosus without manifest cardiovascular…
Comparison
Systemic lupus erythematosus (disease state) vs Healthy controls
Design
Case-control
Authors
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May signal premature vascular aging in postmenopausal SLE; hypothesis-generating for CV risk stratification.
Case-Control (n=94)
Does systemic lupus erythematosus increase arterial stiffness in postmenopausal women without manifest cardiovascular disease?
p-value: p=0.01
Postmenopausal women with SLE without manifest cardiovascular disease exhibit increased arterial stiffness and signs of premature vascular aging compared to healthy controls.
Brodszki et al. (2004) conducted a case-control in Systemic lupus erythematosus (n=94). Systemic lupus erythematosus vs. Healthy controls was evaluated on Stiffness of the abdominal aorta, common carotid artery (CCA) and popliteal artery (PA) (p=0.01). Systemic lupus erythematosus was independently associated with increased arterial stiffness in the common carotid artery (P=0.01) and popliteal artery (P=0.005) compared to healthy controls.
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