Key result
SLE-specific risk factors were associated with increased aortic pulse wave velocity (mean 6.1 +/- 1.7 m/s) in women with systemic lupus erythematosus, particularly among premenopausal women.
Cross-Sectional (n=220)
SLE-specific inflammatory variables are associated with increased central artery stiffening in premenopausal women, which may partially explain their higher cardiovascular risk.
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Highlights potential early vascular changes in premenopausal SLE; hypothesis-generating for inflammation-targeted interventions, pending longitudinal data.
Selzer et al. (2001) conducted a cross-sectional in Systemic Lupus Erythematosus (n=220). SLE-specific and traditional risk factors was evaluated on Aortic stiffness measured by pulse wave velocity (PWV). SLE-specific risk factors were associated with increased aortic pulse wave velocity (mean 6.1 +/- 1.7 m/s) in women with systemic lupus erythematosus, particularly among premenopausal women.
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