Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org
Key result
Asian patients with TIA or minor stroke had similar 1-year rates of composite cardiovascular events compared to non-Asians (6.8% vs 6.0%; P=0.38), but a lower risk of cerebrovascular disease.
Why the study?
Do clinical outcomes and predictors of stroke recurrence differ between Asian and non-Asian patients following a TIA or minor stroke?
Population
4,789 patients (1,149 Asians and 3,640 non-Asians) with a TIA or minor ischemic stroke within 7 days of onset
Comparison
Asian race/ethnicity vs Non-Asian race/ethnicity
Design
Cohort
Follow-up
1 year
Authors
Discussion
Loading...
Member takes
Implication
Findings support uniform post-TIA cardiovascular risk assessment across ethnicities; leaves open ethnicity-specific cerebrovascular predictors pending prospective validation.
Study Design
Type
Cohort (n=4,789)
Multicenter
Yes
Structured PICO
Do clinical outcomes and predictors of stroke recurrence differ between Asian and non-Asian patients following a TIA or minor stroke?
P
Population
4,789 patients (1,149 Asians and 3,640 non-Asians) with a TIA or minor ischemic stroke within 7 days of onset, followed for 1 year.
E
Exposure
Asian race/ethnicity
C
Comparator
Non-Asian race/ethnicity
O
Outcome
Composite of cardiovascular death, nonfatal stroke, and nonfatal acute coronary syndrome at 1 yearcomposite
Main Result
Absolute Event Rate: 6.8% vs 6%
p-value: p=0.38
Following TIA or minor stroke, Asians and non-Asians have similar 1-year composite cardiovascular event rates, but Asians have a lower risk of recurrent TIA and different independent predictors for stroke recurrence.
Cite This Study
Hoshino et al. (2017) conducted a cohort in TIA or minor ischemic stroke (n=4,789). Asian race/ethnicity vs. Non-Asian race/ethnicity was evaluated on composite of cardiovascular death, nonfatal stroke, and nonfatal acute coronary syndrome (p=0.38). Asian patients with TIA or minor stroke had similar 1-year rates of composite cardiovascular events compared to non-Asians (6.8% vs 6.0%; P=0.38), but a lower risk of cerebrovascular disease.