Key result
Asian patients with recent TIA or minor stroke had a similar 5-year risk of cardiovascular death, nonfatal stroke, and nonfatal ACS as non-Asian patients (14.0% vs 11.7%; HR 1.10; p=0.41).
Why the study?
Long-term vascular outcomes in Asian patients with TIA or minor ischemic stroke compared with non-Asian patients in the context of modern guideline-based prevention strategies had not been established.
Does the long-term risk of vascular events differ between Asian and non-Asian patients following a recent TIA or minor ischemic stroke?
Cohort (n=3,847)
Yes
Does the long-term risk of vascular events differ between Asian and non-Asian patients following a recent TIA or minor ischemic stroke?
Hazard Ratio: 1.1 (95% CI 0.88–1.37)
Absolute Event Rate: 14% vs 11.7%
p-value: p=0.41
Asian patients with TIA or minor stroke have a similar 5-year risk of major cardiovascular events as non-Asian patients, but a significantly higher risk of intracranial hemorrhage.
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Highlights the need for tailored secondary prevention strategies in diverse populations; leaves open whether race-specific risk.
Hoshino et al. (2020) conducted a cohort in TIA or minor ischemic stroke (n=3,847). Asian race vs. Non-Asian race was evaluated on Composite of cardiovascular death, nonfatal stroke, and nonfatal acute coronary syndrome (HR 1.10, 95% CI 0.88-1.37, p=0.41). Asian patients with recent TIA or minor stroke had a similar 5-year risk of cardiovascular death, nonfatal stroke, and nonfatal ACS as non-Asian patients (14.0% vs 11.7%; HR 1.10; p=0.41).
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