Why the study?
Does thrombolytic therapy improve outcomes in patients with acute pulmonary embolism?
Population
Patients with acute pulmonary embolism (massive and submassive)
Design
Review
Authors
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Supports selective thrombolysis in massive PE; leaves open optimal submassive strategies pending randomized data.
Does thrombolytic therapy improve outcomes in patients with acute pulmonary embolism?
Thrombolytic therapy is potentially lifesaving for massive acute pulmonary embolism, but requires careful risk stratification due to significant bleeding risks, especially in submassive cases.
Victor F. Tapson (2013) studied this question.
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