Key result
Conventional low-dose heparin was the most cost-effective thromboembolic prophylaxis compared to no prophylaxis, yielding incremental savings of $6087 per mortality avoided.
Why the study?
Does conventional low-dose heparin, dalteparin, or intermittent pneumatic compression improve cost-effectiveness by reducing mortality and complications compared to no prophylaxis in moderate-risk patients undergoing elective abdominal surgery?
Population
Patients at moderate risk of developing thromboembolic complications after major elective abdominal surgery
Comparison
Conventional low-dose heparin, dalteparin, and… vs No prophylaxis
Design
Other
Authors
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May support low-dose heparin prophylaxis in moderate-risk abdominal surgery; leaves open need for randomized confirmation of mortality and cost benefits.
Does conventional low-dose heparin, dalteparin, or intermittent pneumatic compression improve cost-effectiveness by reducing mortality and complications compared to no prophylaxis in moderate-risk patients undergoing elective abdominal surgery?
Conventional low-dose heparin provides the most cost-effective thromboembolic prophylaxis in moderate-risk patients undergoing elective abdominal surgery.
Mamdani et al. (1996) studied Moderate risk of thromboembolic complications after major elective abdominal surgery. Conventional low-dose heparin, dalteparin, and intermittent pneumatic compression vs. No prophylaxis was evaluated on Cost-effectiveness (costs/complication-free patient and cost/mortality avoided). Conventional low-dose heparin was the most cost-effective thromboembolic prophylaxis compared to no prophylaxis, yielding incremental savings of $6087 per mortality avoided.
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