Key result
DVT prophylaxis cuts deaths ~50% vs no prophylaxis in major orthopedic surgery and saves costs.
Why the study?
Multiple prophylaxis methods can reduce postoperative deep-vein thrombosis in major orthopedic surgery, but their cost-effectiveness requires evaluation.
Does prophylaxis against deep-vein thrombosis reduce mortality and healthcare costs in patients undergoing major orthopedic surgery?
Population
Patients undergoing major orthopedic surgery
Comparison
Various prophylaxis methods vs clinical diagnosis and treatment only
Design
Decision analysis
Authors
Loading...
Supports DVT prophylaxis consideration in major orthopedic surgery; leaves open confirmation of mortality benefit in higher-level trials.
Does prophylaxis against deep-vein thrombosis reduce mortality and healthcare costs in patients undergoing major orthopedic surgery?
Prophylaxis against deep-vein thrombosis in major orthopedic surgery is both life-saving and cost-saving compared to no prophylaxis.
G. Oster (1987) studied Deep-vein thrombosis in major orthopedic surgery. Prophylaxis against deep-vein thrombosis (e.g., warfarin, heparin, compression stockings) vs. Clinical diagnosis and treatment only was evaluated on Deaths and average costs of care. Prophylaxis against deep-vein thrombosis in major orthopedic surgery reduces deaths by at least half compared to no prophylaxis (153 deaths per 10,000) and saves $19.40 to $181.60 per patient.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: