Key result
Obesity in young GERD patients is linked to worse symptom severity and quality of life.
Why the study?
Does comorbid obesity worsen clinical symptoms and quality of life in young patients with GERD?
Observational (n=130)
No
Does comorbid obesity worsen clinical symptoms and quality of life in young patients with GERD?
Absolute Event Rate: 45.7% vs 40.2%
p-value: p=<0.05
Comorbid obesity in young patients with GERD is associated with more severe clinical symptoms and a significantly greater negative impact on quality of life.
May prompt obesity assessment in young GERD; leaves open whether weight loss improves outcomes prospectively.
The article analyzes clinical and anamnestic features of patients with gastroesophageal reflex disease with concomitant obesity in young people. Correlations between clinical manifestations and the presence of concomitant pathology and risk factors are established.
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Oparin et al. (2025) conducted an observational in Gastroesophageal reflux disease (GERD) with concomitant obesity (n=130). Concomitant obesity vs. Isolated GERD (without obesity) was evaluated on Total GERD-HRQL score (impact of GERD symptoms on daily life) (p=<0.05). Concomitant obesity in young GERD patients significantly worsens symptom severity and quality of life, reflected by a higher total GERD-HRQL score (45.70) compared to non-obese GERD patients (40.20).
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