Key result
Torso meshes constructed without imposing electrodes as nodes require at least 400 homogeneously distributed nodes (distance <4 cm) to maintain electrocardiographic imaging accuracy.
Why the study?
The study investigated how geometrical mesh node density and recording electrode distribution influence electrocardiographic imaging accuracy during AF.
The effect of mesh density in electrocardiographic imaging is minimal when electrode locations are preserved as nodes, but otherwise torso meshes should contain at least 400 homogeneously distributed nodes.
Answers are grounded in this paper and cite their sources.
Torso mesh density warrants attention in ECGI without electrode nodes; leaves open standardization before clinical adoption.
Introduction: Electrocardiographic Imaging (ECGI) allows computing the electrical activity in the heart non-invasively using geometrical information of the patient and multiple body surface signals. In the present study we investigate the influence of the number of nodes of geometrical meshes and recording ECG electrodes distribution to compute ECGI during atrial fibrillation (AF). Methods: Torso meshes from 100 to 2000 nodes heterogeneously and homogeneously distributed were compared. Signals from nine AF realistic mathematical simulations were used for computing the ECGI. Results for each torso mesh were compared with the ECGI computed with a 4,000 nodes reference torso. In addition, real AF recordings from 25 AF patients were used to compute ECGI in torso meshes from 100 to 1,000 nodes. Results were compared with a reference torso of 2000 nodes. Torsos were remeshed either by reducing the number of nodes while maximizing the overall shape preservation and then assigning the location of the electrodes as the closest node in the new mesh or by forcing the remesher to place a node at each electrode location. Correlation coefficients, relative difference measurements and relative difference of dominant frequencies were computed to evaluate the impact on signal morphology of each torso mesh. Results: For remeshed torsos where electrodes match with a geometrical node in the mesh, all mesh densities presented similar results. On the other hand, in torsos with electrodes assigned to closest nodes in remeshed geometries performance metrics were dependent on mesh densities, with correlation coefficients ranging from 0.53 ± 0.06 to 0.92 ± 0.04 in simulations or from 0.42 ± 0.38 to 0.89 ± 0.2 in patients. Dominant frequency relative errors showed the same trend with values from 1.14 ± 0.26 to 0.55 ± 0.21 Hz in simulations and from 0.91 ± 0.56 to 0.45 ± 0.41 Hz in patients. Conclusion: The effect of mesh density in ECGI is minimal when the location of the electrode is preserved as a node in the mesh. Torso meshes constructed without imposing electrodes to constitute nodes in the torso geometry should contain at least 400 nodes homogeneously distributed so that a distance between nodes is below 4 cm.
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Molero et al. (2022) studied Atrial fibrillation (n=25). Torso mesh density reduction and electrode relocation vs. Reference torso mesh of 2000-4000 nodes was evaluated on Correlation coefficients and relative difference measurements of electrocardiographic imaging signals. Torso meshes constructed without imposing electrodes as nodes require at least 400 homogeneously distributed nodes (distance <4 cm) to maintain electrocardiographic imaging accuracy.
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