Key result
A systemic circulatory model incorporating a modified atrioventricular piston unit accurately reproduced realistic pressure-flow relationships in the LV chamber with a root mean squared error of 2.99 mmHg.
Why the study?
The contribution of longitudinal atrioventricular plane displacement to ventricular pumping has drawn increasing attention.
Does a switched system model based on a modified atrioventricular piston unit accurately reproduce realistic pressure-flow relationships in the LV chamber?
Population
1 patient undergoing routine diagnostic cardiac catheterization with LV angiography
Comparison
Estimated LV pressure from a switched system circulatory model vs measured clinical data
Design
Computational modeling and validation study
Authors
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May aid preclinical device testing; leaves open clinical translation pending human validation.
Does a switched system model based on a modified atrioventricular piston unit accurately reproduce realistic pressure-flow relationships in the LV chamber?
A novel computational model incorporating longitudinal atrioventricular plane displacement accurately reproduces realistic left ventricular pressure-flow relationships.
Huang et al. (2018) studied this question. Modified atrioventricular piston unit model vs. Measured LV pressure was evaluated on Root mean squared error between measured and estimated LV pressure. A systemic circulatory model incorporating a modified atrioventricular piston unit accurately reproduced realistic pressure-flow relationships in the LV chamber with a root mean squared error of 2.99 mmHg.
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