Why the study?
Does treatment of hyperlipidemia and hypertension improve vascular structure and endothelial function in atherosclerotic and hypertensive vessels?
Does treatment of hyperlipidemia and hypertension improve vascular structure and endothelial function in atherosclerotic and hypertensive vessels?
Effective treatment of hyperlipidemia and hypertension can reverse structural and functional abnormalities in atherosclerotic and hypertensive vessels, with pulse pressure reduction potentially playing a key role.
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Supports vascular benefits of lipid-lowering and ACE inhibitor therapy; leaves open pulse pressure's role in remodeling.
Heistad et al. (1995) studied this question.
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