January 1, 2015Thrombosis and Haemostasis
Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants
Key result
This document is a journal masthead and contains no clinical study data.
Population
Patients receiving non-vitamin K antagonist oral anticoagulants for the prevention and treatment of venous…
Design
Review
Authors
Discussion
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Member takes
Implication
Provides practical guidance for NOAC bleeding management; leaves open need for dedicated reversal trials.
Structured PICO
P
Population
Patients receiving non-vitamin K antagonist oral anticoagulants (NOACs) for the prevention and treatment of venous thromboembolism and prevention of stroke in non-valvular atrial fibrillation
I
Intervention
Management protocols for NOAC-related bleeding (including temporarily withholding treatment, escalating haemodynamic support measures, and non-specific reversal agents)
This review provides practical guidance on managing NOAC-related bleeding, emphasizing that while specific reversal agents are lacking, outcomes are generally similar or better than with VKAs, and mild bleeding can often be managed simply by withholding the drug.
Cite This Study
Pollack et al. (2015) studied this question. This document is a journal masthead and contains no clinical study data.