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May 1, 1989Journal of Biological ChemistryOpen Access

Sphingomyelinase action inhibits phorbol ester-induced differentiation of human promyelocytic leukemic (HL-60) cells

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RKRichard KolesnickMemorial Sloan Kettering Cancer Center

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Richard Kolesnick (1989) studied this question.

synapsesocial.com/papers/6a207ad404d2adee4bf493dfhttps://doi.org/10.1016/s0021-9258(18)83279-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 11,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase.1988 · 117 citations
  2. 2Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages.1978 · 240 citations
  3. 3Nonspecific acid esterase activity: A criterion for differentation of T and B lymphocytes in mouse lymph nodes1975 · 445 citations
  4. 4Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.1986 · 312 citations
  5. 5Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.1987 · 155 citations