Key result
Adult canine extraocular rectus muscles express embryonic skeletal/atrial MLC1 in slow fibers of the orbital layer, while slow-type MLC1 is expressed in slow fibers of the global layer.
Authors
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Does not yet alter clinical strabismus management; leaves open translational relevance of canine MLC1 patterns to human ocular motility.
Bicer et al. (2003) studied this question. Global vs orbital layers of canine rectus muscles was evaluated on MLC1 isoform expression pattern. Adult canine extraocular rectus muscles express embryonic skeletal/atrial MLC1 in slow fibers of the orbital layer, while slow-type MLC1 is expressed in slow fibers of the global layer.
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