March 4, 2015Critical Care Medicine
Extracorporeal Membrane Oxygenation for the Support of Adults With Acute Myocarditis
Key result
Among adults with acute myocarditis supported with ECMO, survival to hospital discharge was 61%, and pre-ECMO cardiac arrest was associated with increased in-hospital mortality (OR 2.4; 95% CI 1.1-5.0).
Why the study?
What are the survival outcomes and risk factors for in-hospital mortality in adult patients with acute myocarditis supported with extracorporeal membrane oxygenation?
Population
147 patients 16 years old or older with a diagnosis of acute myocarditis supported with extracorporeal…
Design
Cohort
Follow-up
to hospital discharge
Authors
Discussion
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Member takes
Implication
May aid prognostic counseling for myocarditis ECMO; leaves open prospective validation of mortality predictors.
Study Design
Type
Cohort (n=147)
Multicenter
Yes
Structured PICO
What are the survival outcomes and risk factors for in-hospital mortality in adult patients with acute myocarditis supported with extracorporeal membrane oxygenation?
P
Population
147 patients aged 16 years or older with acute myocarditis supported with extracorporeal membrane oxygenation across 230 centers from 1995 to 2011.
E
Exposure
Extracorporeal membrane oxygenation (ECMO)
O
Outcome
Survival to hospital dischargehard clinical
In adults with acute myocarditis, ECMO support resulted in a 61% survival to hospital discharge, with pre-ECMO cardiac arrest and on-ECMO adverse events significantly increasing mortality risk.
Cite This Study
Diddle et al. (2015) conducted a cohort in Acute myocarditis (n=147). Extracorporeal membrane oxygenation was evaluated on Survival to hospital discharge. Among adults with acute myocarditis supported with ECMO, survival to hospital discharge was 61%, and pre-ECMO cardiac arrest was associated with increased in-hospital mortality (OR 2.4; 95% CI 1.1-5.0).