High-Dose Immunoglobulin G Therapy for Fulminant Myocarditis
Why the study?
Does intravenous high-dose immunoglobulin G improve cardiac function in an adult patient with fulminant myocarditis requiring mechanical circulatory support?
Population
1 adult patient with fulminant myocarditis requiring mechanical circulatory support
Design
Case_report
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for IVIG in fulminant myocarditis on MCS; controlled trials needed before any practice change.
Structured PICO
Does intravenous high-dose immunoglobulin G improve cardiac function in an adult patient with fulminant myocarditis requiring mechanical circulatory support?
P
Population
1 adult patient with fulminant myocarditis requiring mechanical circulatory support
I
Intervention
Intravenous infusion with high-dose immunoglobulin G
O
Outcome
Improvement in cardiac function and suppression of inflammatory mediatorssurrogate
High-dose intravenous immunoglobulin may serve as a potential adjunctive therapy for fulminant myocarditis by improving cardiac function and suppressing inflammatory mediators.
Cite This Study
Takeda et al. (1998) studied this question.