Key result
Preeclampsia was associated with significantly higher serum Nt pro-BNP levels compared to normotensive pregnancy (430 vs 74 pg/mL; P<0.001).
Why the study?
Are serum Nt pro-BNP levels higher in women with preeclampsia compared to normotensive pregnant women?
Population
80 pregnant women, including 40 with preeclampsia and 40 normotensive women.
Comparison
Preeclampsia vs Normotensive pregnancy
Design
Case-control
Authors
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May indicate subclinical cardiac strain; hypothesis-generating for prognostic validation in prospective cohorts.
Case-Control (n=80)
Are serum Nt pro-BNP levels higher in women with preeclampsia compared to normotensive pregnant women?
Absolute Event Rate: 430% vs 74%
p-value: p=<0.001
Serum Nt pro-BNP levels are significantly elevated in preeclampsia compared to normotensive pregnancy, potentially indicating high left-ventricular filling pressure and diastolic dysfunction.
Kale et al. (2005) conducted a case-control in Preeclampsia (n=80). Preeclampsia vs. Normotensive pregnancy was evaluated on Serum Nt pro-BNP levels (p=<0.001). Preeclampsia was associated with significantly higher serum Nt pro-BNP levels compared to normotensive pregnancy (430 vs 74 pg/mL; P<0.001).
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