January 1, 2001Hypertension in Pregnancy

Amino-Terminal Pro-Brain Natriuretic Peptide in Normal and Hypertensive Pregnancy

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Why the study?

Are serum Nt pro-BNP levels elevated in pregnancies complicated by hypertension compared to normal pregnancies?

Population

66 pregnant women, including 24 with hypertension in pregnancy and 42 normotensive women.

Design

Cross-sectional

Authors

SFS FlemingMerck & Co., Inc., Rahway, NJ, USA (United States)LOLourde O’ByrneUniversity Hospital Galway HGHelen GrimesUniversity College Hospital

Discussion

Member takes

Implication

Should not yet change monitoring of hypertensive pregnancies; hypothesis-generating for Nt pro-BNP as cardiac strain marker pending prospective studies.

Structured PICO

Are serum Nt pro-BNP levels elevated in pregnancies complicated by hypertension compared to normal pregnancies?

Population

66 pregnant women, including 24 with hypertension in pregnancy (at least two readings of systolic blood pressure > 140 mm Hg and diastolic blood pressure > 90 mm Hg) and 42 normotensive women.

Outcome

Serum amino-terminal pro-brain natriuretic peptide (Nt pro-BNP) levelssurrogate

Serum Nt pro-BNP is elevated in hypertensive disorders of pregnancy and is higher in multigravida than primigravida women, suggesting elevated left-ventricular filling pressures.

Cite This Study

Fleming et al. (2001) studied this question.

synapsesocial.com/papers/6a767d8a46f688d752c44917 https://doi.org/10.1081/prg-100106966

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Should not yet change monitoring of hypertensive pregnancies; hypothesis-generating for Nt pro-BNP as cardiac strain marker pending prospective studies.

Amino-Terminal Pro-Brain Natriuretic Peptide in Normal and Hypertensive Pregnancy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Amino-Terminal Pro-Brain Natriuretic Peptide in Normal and Hypertensive Pregnancy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider