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April 1, 2019MedicineOpen Access

Association between heart rate on admission and in-hospital mortality among general inpatients

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Key result

Higher heart rate on admission was associated with increased in-hospital mortality, with an adjusted odds ratio of 3.64 (95% CI 1.88-7.05) for HR ≥100 bpm in medical wards.

Why the study?

The association between heart rate and in-hospital mortality in general patients regardless of underlying diseases had not been well scrutinized.

Is higher heart rate on admission associated with increased in-hospital mortality among general inpatients?

Population

2360 general inpatients aged ≥12 years at a tertiary care hospital in Japan

Comparison

Five admission heart rate categories (<60, 60-79, 80-99, 100-119, and ≥120 bpm)

Design

Single-center prospective cohort study

Follow-up

During hospitalization

Authors

MYMarumi YamamotoNational Archives and Records AdministrationYOYoshinori OhtaKyoto Medical CenterMSMio SakumaMukogawa Women's University

Discussion

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Member takes

Implication

May flag high-risk general inpatients for monitoring; hypothesis-generating and requires prospective confirmation before practice change.

Study Design

Type

Cohort (n=2,360)

Multicenter

No

Structured PICO

Is higher heart rate on admission associated with increased in-hospital mortality among general inpatients?

P
Population
2,360 general inpatients aged ≥12 years admitted to a tertiary care hospital in Japan, excluding pregnant women.
E
Exposure
Heart rate on admission (categorized into <60, 60-79, 80-99, 100-119, ≥120 bpm)
C
Comparator
Lower heart rate groups
O
Outcome
In-hospital mortalityhard clinical

Main Result

Odds Ratio: 3.64 (95% CI 1.88–7.05)

p-value: p=<.001

Higher heart rate on admission (≥100 bpm in medical wards, ≥120 bpm in surgical wards) is significantly associated with increased in-hospital mortality among general inpatients.

Cite This Study

Yamamoto et al. (2019) conducted a cohort in general inpatients (n=2,360). Heart rate on admission vs. Lower heart rate was evaluated on in-hospital mortality (OR 3.64, 95% CI 1.88-7.05, p=<.001). Higher heart rate on admission was associated with increased in-hospital mortality, with an adjusted odds ratio of 3.64 (95% CI 1.88-7.05) for HR ≥100 bpm in medical wards.

synapsesocial.com/papers/6a207d11ca5c5b2ddfa5dfebhttps://doi.org/10.1097/md.0000000000015165
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