Key result
Age-related physiologic changes in organ systems impair the ability of older patients with cancer to tolerate therapy and increase their risk of toxicities.
Why the study?
How do age-related physiologic changes impact cancer treatment tolerance and toxicity in elderly patients?
Population
Elderly patients with cancer
Design
Review
Authors
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Age-related changes warrant cautious dosing and monitoring in older cancer patients; leaves open optimal geriatric-specific strategies for prospective validation.
How do age-related physiologic changes impact cancer treatment tolerance and toxicity in elderly patients?
Understanding age-related physiologic changes is crucial for oncologists to tailor cancer treatments and manage toxicities in the growing population of elderly patients.
Sawhney et al. (2005) conducted a review in Cancer in elderly patients. Age-related physiologic changes was evaluated. Age-related physiologic changes in organ systems impair the ability of older patients with cancer to tolerate therapy and increase their risk of toxicities.
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