Key result
Deep subcutaneous adipose tissue correlated with hepatic fat content (standardized β=0.190, P<0.05), while in women with obesity, superficial SAT correlated negatively with hepatic fat (β=-0.300, P=0.04).
Why the study?
Subcutaneous adipose tissue is not homogeneous, and the study sought to evaluate sex-specific associations of superficial and deep subcutaneous adipose tissue with hepatic steatosis and metabolic syndrome in overweight individuals.
Cross-Sectional (n=285)
Effect estimate: standardized β = 0.190
p-value: p=<.05
Deep and superficial subcutaneous adipose tissue compartments have sex-specific associations with hepatic steatosis and metabolic traits, with deep SAT linked to adverse traits in men and superficial SAT linked to beneficial traits in women.
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May inform sex-stratified steatosis risk assessment; hypothesis-generating pending prospective validation.
Brand et al. (2021) conducted a cross-sectional in Hepatic steatosis and metabolic syndrome (n=285). Deep and superficial subcutaneous adipose tissue was evaluated on Hepatic fat content (standardized β = 0.190, p=<.05). Deep subcutaneous adipose tissue correlated with hepatic fat content (standardized β=0.190, P<0.05), while in women with obesity, superficial SAT correlated negatively with hepatic fat (β=-0.300, P=0.04).
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