Abdominal Superficial Subcutaneous Fat
Key result
Increased percentage of abdominal superficial subcutaneous fat was significantly associated with decreased HbA1c (β = -0.317; P = 0.013) and daytime ambulatory blood pressure (β = -0.426; P = 0.008).
Why the study?
Is increased abdominal superficial subcutaneous fat associated with improved cardiometabolic parameters in patients with type 2 diabetes?
Population
73 patients with type 2 diabetes, mean age 58 years, 83% men.
Comparison
Increased absolute amount or proportion of… vs Lower amount/proportion of SSAT, or deep…
Design
Cross-sectional
Authors
Discussion
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Implication
May inform fat distribution research in T2D; leaves open causality and precludes practice change.
Study Design
Type
Cross-Sectional (n=73)
Structured PICO
Is increased abdominal superficial subcutaneous fat associated with improved cardiometabolic parameters in patients with type 2 diabetes?
P
Population
73 patients with type 2 diabetes, mean age 58 years, 83% men.
I
Intervention
Increased absolute amount or proportion of abdominal superficial subcutaneous fat (SSAT) measured by MRI
C
Comparator
Lower amount/proportion of SSAT, or deep subcutaneous adipose tissue (DSAT)
O
Outcome
Cardiometabolic parameters including fasting plasma glucose, HbA1c, ambulatory blood pressure, and HDL cholesterolsurrogate
Main Result
Effect estimate: β = -0.317
p-value: p=0.013
In patients with type 2 diabetes, a higher proportion of abdominal superficial subcutaneous fat is associated with a more favorable cardiometabolic profile, including lower HbA1c and blood pressure.
Cite This Study
Golan et al. (2012) conducted a cross-sectional in Type 2 diabetes (n=73). Abdominal superficial subcutaneous fat (SSAT) was evaluated on HbA1c (β = -0.317, p=0.013). Increased percentage of abdominal superficial subcutaneous fat was significantly associated with decreased HbA1c (β = -0.317; P = 0.013) and daytime ambulatory blood pressure (β = -0.426; P = 0.008).