Why the study?
Does a 75-g oral glucose tolerance test affect muscle sympathetic nerve activity differently based on body fat and race in men?
Population
31 men, matched for body fat and age, covering a large range of body weight and body fat
Design
Cross-sectional
Authors
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Higher body fat blunts MSNA response to oral glucose independently of race; leaves open whether this marks obesity/insulin resistance syndrome.
Does a 75-g oral glucose tolerance test affect muscle sympathetic nerve activity differently based on body fat and race in men?
Obesity is associated with higher fasting sympathetic neural outflow to muscle but a blunted increase in response to an oral glucose load, which may represent a feature of the obesity/insulin resistance syndrome.
Spraul et al. (1994) studied this question.
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