Key result
Roux-en-Y gastric bypass surgery resulted in a significantly greater increase in forced vital capacity compared to intensive lifestyle intervention (mean difference 7%; 95% CI 4-10%).
Why the study?
Does Roux-en-Y gastric bypass surgery improve pulmonary function and arterial blood gases compared to intensive lifestyle intervention in morbidly obese subjects?
Population
139 morbidly obese subjects (19-66 years, mean BMI 45.1 kg/m2, 107 women)
Comparison
Roux-en-Y gastric bypass surgery vs Intensive lifestyle intervention
Design
Cohort, non-randomized
Follow-up
1 year
Authors
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May support RYGB over lifestyle intervention for lung function in obesity; hypothesis-generating and requires RCTs before practice change.
Does Roux-en-Y gastric bypass surgery improve pulmonary function and arterial blood gases compared to intensive lifestyle intervention in morbidly obese subjects?
Mean Difference: 7 (95% CI 4–10)
Gastric bypass surgery is more effective than intensive lifestyle intervention at improving pulmonary function and arterial oxygenation in morbidly obese patients, likely mediated by greater weight loss.
Gabrielsen et al. (2013) studied Morbid obesity (n=139). Roux-en-Y gastric bypass surgery vs. Intensive lifestyle intervention was evaluated on Forced vital capacity (MD 7%, 95% CI 4-10). Roux-en-Y gastric bypass surgery resulted in a significantly greater increase in forced vital capacity compared to intensive lifestyle intervention (mean difference 7%; 95% CI 4-10%).
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