Key result
Roux-en-Y gastric bypass boosts relative VO2max by ~38% at 18 months despite declining absolute fitness.
Why the study?
The impact of Roux-en-Y gastric bypass on cardiopulmonary fitness in obese patients before and after surgery was investigated to understand changes in fitness and exercise habits.
Does Roux-en-Y gastric bypass improve cardiopulmonary fitness in obese patients?
Cohort (n=34)
Does Roux-en-Y gastric bypass improve cardiopulmonary fitness in obese patients?
Absolute Event Rate: 29% vs 21%
p-value: p=<0.001
While relative cardiopulmonary fitness improves after gastric bypass due to weight loss, absolute fitness decreases, highlighting the need for structured exercise programs post-surgery.
Roux‐en‐Y gastric bypass (RYGB) leads to a major weight loss in obese patients. However, given that most patients remain obese after the weight loss, regular exercise should be part of a healthier lifestyle. The primary aim of this study was to investigate the cardiopulmonary fitness in obese patients before and after RYGB. Thirty‐four patients had body composition and cardiopulmonary fitness (VO2max) assessed and completed questionnaires regarding physical activity and function twice before RYGB (time points A and B) and 4 and 18 months after surgery (time points C and D). Weight loss was 37 ± 2 kg during the study period. VO2max increased (A: 21 ± 1 vs D: 29 mL/min/kg, P < 0.001), but absolute VO2max decreased (A: 2713 ± 126 vs 2609 ± 187 mL/min, P = 0.02) and VO2max per kilogram fat free mass did not change. Self‐perceived limitations to perform exercise decreased and self‐perceived physical fitness increased after RYGB. Self‐reported low‐ and high‐intensity physical activity did not change. With weight loss, self‐rated fitness level increased and the limitations to perform exercise decreased in RYGB patients. Nevertheless, as shown by the lower absolute VO2max, RYGB patients do not adopt new exercise habits following surgery.
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Lund et al. (2015) conducted a cohort in Obesity (n=34). Roux-en-Y gastric bypass vs. Pre-surgery baseline was evaluated on Cardiopulmonary fitness (VO2max in mL/min/kg) (p=<0.001). Roux-en-Y gastric bypass increased relative VO2max (21 vs 29 mL/min/kg, P<0.001) but decreased absolute VO2max (2713 vs 2609 mL/min, P=0.02) at 18 months, suggesting no new exercise habits.
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