Computerized ST Depression Analysis Improves Prediction of All‐Cause and Cardiovascular Mortality: The Strong Heart Study
Key result
Computerized Minnesota coding and computer-measured ST depression independently predicted cardiovascular mortality (RR 3.0, 95% CI 1.6-5.6 and RR 3.1, 95% CI 1.7-5.7), outperforming visual coding.
Why the study?
Does computerized ST depression analysis improve prediction of cardiovascular and all-cause mortality compared to visual Minnesota coding in American Indian participants?
Population
2,127 American Indian participants in the first Strong Heart Study examination
Comparison
Computerized Minnesota coding codes 4.2 or 4.3… vs Standard visual Minnesota coding codes 4.2 or…
Design
Cohort
Follow-up
mean 3.7 +/- 0.9 years
Authors
Discussion
Loading...
Member takes
Implication
May support computerized ECG coding for CV mortality stratification; hypothesis-generating in this cohort and requires prospective validation.
Study Design
Type
Cohort (n=2,127)
Structured PICO
Does computerized ST depression analysis improve prediction of cardiovascular and all-cause mortality compared to visual Minnesota coding in American Indian participants?
P
Population
2,127 American Indian participants followed for a mean of 3.7 years to assess the prognostic value of computerized ST depression analysis for mortality.
E
Exposure
Computerized Minnesota coding (MC) codes 4.2 or 4.3 and computer-measured ST depression ≥ 50 microV
C
Comparator
Standard visual Minnesota coding (MC) codes 4.2 or 4.3 performed by an experienced ECG core laboratory
O
Outcome
Cardiovascular mortality at mean 3.7 years follow-uphard clinical
Main Result
Relative Risk: 3 (95% CI 1.6–5.6)
Computerized ST depression analysis provides independent and superior risk stratification for cardiovascular and all-cause mortality compared to standard visual Minnesota coding.
Cite This Study
Okin et al. (2001) conducted a cohort in Cardiovascular risk (n=2,127). Computerized Minnesota coding and computer-measured ST depression vs. Standard visual Minnesota coding was evaluated on Cardiovascular mortality (RR 3.0, 95% CI 1.6-5.6). Computerized Minnesota coding and computer-measured ST depression independently predicted cardiovascular mortality (RR 3.0, 95% CI 1.6-5.6 and RR 3.1, 95% CI 1.7-5.7), outperforming visual coding.