Key result
Pan Immune-Inflammation Value and Systemic Immune-Inflammation Index were independent predictors of MACE in patients undergoing PCI for unprotected LMCA disease (P=0.045 and P=0.048, respectively).
Why the study?
Long-term prognostic factors including inflammatory parameters like Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII) for PCI in unprotected LMCA disease were not well defined.
Do Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII) predict MACE in patients undergoing unprotected LMCA PCI?
Observational (n=121)
Do Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII) predict MACE in patients undergoing unprotected LMCA PCI?
Inflammatory parameters like PIV and SII can serve as independent prognostic markers for MACE in patients undergoing unprotected LMCA PCI.
Aim: This study aimed long-term prognostic factors for percutaneous coronary intervention (PCI) in left main coronary artery (LMCA) disease, focusing on inflammatory parameters like Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII).Materials & methods: This retrospective, observational study involved 121 patients receiving unprotected LMCA PCI.The study's primary end point was MACE, including all-cause death, repeat revascularization and myocardial reinfarction.Results: The PIV and SII scores emerged as independent predictors of MACE occurrence in patients undergoing PCI for unprotected LMCA disease (p:0.045,p:0.048;respectively).In addition, age, ejection fraction, creatinine, shock presentation and the residual syntax score were identified as significant independent predictors of MACE in both models.Conclusion: This study showed a significant, independent correlation between PIV, SII and MACE in patients undergoing PCI for LMCA disease, with PIV showing slightly better predictive capability than SII.
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Karaduman et al. (2024) conducted an observational in Left main coronary artery (LMCA) disease (n=121). Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII) was evaluated on MACE (all-cause death, repeat revascularization, and myocardial reinfarction) (p=0.045 (PIV), 0.048 (SII)). Pan Immune-Inflammation Value and Systemic Immune-Inflammation Index were independent predictors of MACE in patients undergoing PCI for unprotected LMCA disease (P=0.045 and P=0.048, respectively).
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