Key result
Scn1b mRNA and protein show a dynamic expression pattern during mouse heart development, peaking at E12.5, decreasing at E15.5, and increasing again to maximal levels in the adult heart.
Authors
Loading...
Supports investigation of Scn1b in developmental arrhythmias; leaves open clinical translation from mouse models.
Domínguez et al. (2004) studied Mouse cardiac development. Scn1b expression analysis was evaluated on Scn1b mRNA expression levels and protein distribution. Scn1b mRNA and protein show a dynamic expression pattern during mouse heart development, peaking at E12.5, decreasing at E15.5, and increasing again to maximal levels in the adult heart.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: