Key result
Implantation of biodegradable poly-l-lactic acid coronary stents was feasible and safe, with a 6.7% per-patient rate of restenosis and target lesion revascularization at 6 months.
Why the study?
Is the biodegradable poly-l-lactic acid (PLLA) coronary stent feasible, safe, and effective in patients with coronary artery stenoses?
Is the biodegradable poly-l-lactic acid (PLLA) coronary stent feasible, safe, and effective in patients with coronary artery stenoses?
Biodegradable PLLA coronary stents appear feasible and safe in humans up to 6 months, with acceptable restenosis rates and no early stent thrombosis.
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Supports PLLA stent feasibility in case series; leaves open need for RCTs to confirm efficacy versus permanent stents.
Tamai et al. (2000) studied Coronary artery stenoses (n=15). Biodegradable poly-l-lactic acid (PLLA) Igaki-Tamai stent was evaluated on Restenosis rate and target lesion revascularization rate. Implantation of biodegradable poly-l-lactic acid coronary stents was feasible and safe, with a 6.7% per-patient rate of restenosis and target lesion revascularization at 6 months.
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