An experimental implantable defibrillator with a temporary high-output pacing function successfully demonstrated automatic defibrillation and post-shock pacing in a canine model.
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Feasible in canines; leaves open translation to clinical devices with integrated post-shock pacing.
An experimental implantable defibrillator with a temporary pacing function was developed. The pacing function was activated after defibrillation to work as a high-output ventricular-demand pacemaker. The developed system was tested in animal experiments involving anesthesized and mechanically ventilated mongrel dogs. In the animal experiments, fibrillation was electrically induced, and the automatic defibrillation and pacing function were confirmed. After defibrillation, it was possible to continue the fixed-rate pacing for more than three minutes.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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Makino et al. (1988) studied this question.
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