Population
Rabbit fast skeletal muscle (preclinical model)
Comparison
Calmodulin vs Absence of calmodulin; Troponin C
Design
Preclinical
Authors
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No immediate clinical implications from skeletal muscle data; leaves open calmodulin-MLCK mechanisms in cardiac research.
Calmodulin is essential for the activation of myosin light-chain kinase in rabbit fast skeletal muscle, forming a Ca2+-dependent complex.
Nairn et al. (1979) studied this question.
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