Key result
Different definitions of awake-asleep periods and BP indices significantly affected the classification of nocturnal BP dipping (kappa 0.323-0.459) and its relation with target-organ damage.
Why the study?
How do different definitions of awake/asleep periods and BP indices affect the classification of nocturnal BP dipping and its relation to target-organ damage in hypertensive patients?
Cross-Sectional (n=150)
How do different definitions of awake/asleep periods and BP indices affect the classification of nocturnal BP dipping and its relation to target-organ damage in hypertensive patients?
The method used to define awake and asleep periods during 24-hour ambulatory BP monitoring significantly alters the classification of nocturnal dipping and its association with target-organ damage.
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Variable definitions undermine reliable nocturnal dipping assessment; leaves open consensus ABPM protocols for clinical and research use.
Henskens et al. (2008) conducted a cross-sectional in Hypertension (n=150). Different definitions of awake and asleep periods and BP indices vs. Wide diary definition (actual awake and sleep periods) was evaluated on Classification of nocturnal BP dipping and relation with target-organ damage (left ventricular mass index and urinary albumin excretion). Different definitions of awake-asleep periods and BP indices significantly affected the classification of nocturnal BP dipping (kappa 0.323-0.459) and its relation with target-organ damage.
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