Key result
A reproducible non-dipping blood pressure profile was associated with a significantly higher prevalence of left ventricular hypertrophy compared to a dipping profile (19% vs 6%, P<0.05).
Why the study?
Does a reproducible non-dipping blood pressure profile associate with greater target organ damage compared to a reproducible dipping profile in never-treated essential hypertensive patients?
Cross-Sectional (n=375)
Does a reproducible non-dipping blood pressure profile associate with greater target organ damage compared to a reproducible dipping profile in never-treated essential hypertensive patients?
Absolute Event Rate: 19% vs 6%
p-value: p=<0.05
A reproducible non-dipping blood pressure pattern confirmed by two ABPM periods is associated with more pronounced cardiac structural abnormalities in never-treated essential hypertensives.
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May identify higher cardiac risk in untreated hypertensives; hypothesis-generating for ABPM-based stratification pending prospective data.
Cuspidi et al. (2004) conducted a cross-sectional in Essential hypertension (n=375). Reproducible non-dipping blood pressure profile vs. Reproducible dipping blood pressure profile was evaluated on Prevalence of left ventricular hypertrophy (p=<0.05). A reproducible non-dipping blood pressure profile was associated with a significantly higher prevalence of left ventricular hypertrophy compared to a dipping profile (19% vs 6%, P<0.05).
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