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September 1, 2001Journal of Hypertension

Target organ damage and non-dipping pattern defined by two sessions of ambulatory blood pressure monitoring in recently diagnosed essential hypertensive patients

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Why the study?

Does a non-dipping blood pressure pattern associate with increased target organ damage in recently diagnosed essential hypertensive patients?

Population

118 recently diagnosed, never-treated essential hypertensive patients with reproducible dipping or…

Comparison

Non-dipping blood pressure pattern vs Dipping blood pressure pattern

Design

Cross-sectional

Authors

CCCesare CuspidiPreventive CardiologyGMG MaccaASST Melegnano e della MartesanaLSLorena SampieriUniversity of Milan

Discussion

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Implication

Non-dipping pattern associated with more LVH and carotid thickening in new hypertensives; leaves open need for prospective outcome studies.

Structured PICO

Does a non-dipping blood pressure pattern associate with increased target organ damage in recently diagnosed essential hypertensive patients?

P
Population
118 recently diagnosed, never-treated essential hypertensive patients with reproducible dipping (n=92) or non-dipping (n=26) patterns confirmed by two 24 h ambulatory blood pressure monitoring sessions
I
Intervention
Non-dipping blood pressure pattern (≤10% nocturnal fall in systolic and diastolic blood pressure)
C
Comparator
Dipping blood pressure pattern (>10% nocturnal fall in systolic and diastolic blood pressure)
O
Outcome
Target organ damage (prevalence of left ventricular hypertrophy, carotid intima-media thickening, retinal changes, and microalbuminuria)surrogate

A reproducible non-dipping blood pressure pattern is associated with early target organ damage, including left ventricular hypertrophy and carotid intima-media thickening, in recently diagnosed essential hypertension.

Cite This Study

Cuspidi et al. (2001) studied this question.

synapsesocial.com/papers/6a1981f45d70402e70d964bchttps://doi.org/10.1097/00004872-200109000-00004

Topics

Hypertension managementEchocardiography
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Also Consider

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  1. 1Relationship of 24-Hour Blood Pressure Mean and Variability to Severity of Target-Organ Damage in Hypertension1987 · 957 citations
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  4. 4The Role of Carotid Arterial Intima-Media Thickness in Predicting Clinical Coronary Events1998 · 1,224 citations
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